Research summary
A collaborative study examines TRIM37 variant rs57141087 and triple-negative breast cancer outcomes in Black women.
Study context
TRIM37 in breast-cancer outcomes
How do TRIM37 activity and variation relate to difficult breast-cancer outcomes?
How it was studied
The studies use the distinct model systems, molecular assays and population analyses described in their respective articles. Their claims should not be merged into one causal chain.
Selected findings
- The Cancer Research article links oncogenic TRIM37 to chemoresistance and metastatic phenotypes in TNBC models.
- EMBO Reports examines an rs57141087 association and functional context in Black women with TNBC.
Collaborative, coauthored research. Population associations and experimental mechanisms require their original study boundaries.
Authors
Cite this work
Rachisan Djiake Tihagam, Song Lou, Yuanji Zhao, Kammi Song-Yan Liu, Arjun Tushir Singh, Bon Il Koo, Piotr Przanowski, Jie Li, Xiaosong Huang, Hong Li, Jogender Tushir-Singh, Laura Fejerman, Sanchita Bhatnagar (2025). The TRIM37 variant rs57141087 contributes to triple-negative breast cancer outcomes in Black women. EMBO reports, 245-272. https://doi.org/10.1038/s44319-024-00331-2