About

Jogender (Jogi) Tushir-Singh, Ph.D. · Associate Professor, UC Davis School of Medicine

Jogender Tushir-Singh studies how engineered antibodies and immune-cell signals engage cancer-cell death receptors. His laboratory has worked on Fas/CD95, DR5, TIGIT/CD155 and plasmin in ovarian and other solid-tumor models.

His training spans epithelial cell signaling, PIWI/piRNA biochemistry and industrial antibody discovery. He established the Laboratory of Novel Biologics at the University of Virginia in 2015 and moved it to UC Davis in September 2021. The current UC Davis appointment is in Medical Microbiology and Immunology, with affiliations in Gynecologic Oncology and the Comprehensive Cancer Center.

UC Davis biography (external link) · UMass Chan career record (external link)

Education and appointments

University of Delhi

Bachelor of Science.

University of Notre Dame

Ph.D. in Cell and Molecular Biology; doctoral work with Crislyn D’Souza-Schorey on small GTPases and epithelial transitions.

UMass Chan / HHMI

Postdoctoral research with Phillip D. Zamore on Piwi and piRNA biochemistry. Public sources differ on the exact interval.

AbbVie and Boehringer Ingelheim

Senior Scientist and Principal Scientist roles in antibody discovery and protein engineering.

University of Virginia

First independent faculty appointment; antibody engineering and solid-tumor research.

UC Davis School of Medicine

Associate Professor of Medical Microbiology and Immunology.

UC Davis education and appointment record (external link) · UC Davis seminar biography (external link) · UMass Chan alumni biography (external link)

Why ovarian cancer

UC Davis reports that the loss of his grandmother to ovarian cancer shaped his interest in the disease. His program applies antibody humanization, bispecific formats and protein design to death-receptor biology and the different responses of T-cell therapies in solid and liquid tumors.

Research interests at UC Davis (external link)

Selected recognition

  • 2017 · U.S. Department of Defense Breast Cancer Research Breakthrough award
  • 2018 · Ovarian Cancer Academy Early Career Investigator
  • 2020 · Schiff Foundation award
  • 2021 · University of Virginia School of Medicine exceptional research contribution merit list

UC Davis honors list (external link) · Ovarian Cancer Academy report (external link)